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A massive wildfire in Alberta now extends more than 600 square miles, and officials are concerned that it could double in size on Saturday because of windy, dry weather conditions.

The thoroughbred took home the day's biggest victory at Churchill Downs. Now, the crucial question: Can he replicate American Pharoah's feat and add this jewel to an eventual Triple Crown?

One man died and five others were injured in a clinical trial in France this year. Trials like those depend on healthy people willing to take experimental medications in return for cash.

Time is almost up for consumers to tell the FDA what "natural" food means. It's an ancient philosophical question with no easy answers.

NPR's Alice Fordham in Beirut updates Melissa Block about the status of the ceasefire in Aleppo, the al-Qaida affiliate in Syria, which isn't included in the ceasefire, and riots at a jail in Hama.

The Boston Globe

Antonio Pampliega, José Manuel López, and Ángel Sastre crossed into Turkey from its northern border with Turkey last July to report on the fighting in Aleppo. They hadn't been heard from since.

Stargazers, ready your (solar-filtered) telescopes: Mercury is passing directly across the sun Monday for more than seven hours. And you can watch — if you do it just right.

The documentary filmmaker has been chosen to deliver this year's Jefferson Lecture in the Humanities, the highest honor bestowed by the federal government for work in the field.

North Korea's powerful are gathering for their first ruling party congress in decades. Kim Jong Un is working to consolidate his power at home — and regionally — with an expanded nuclear arsenal.