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Research connects measles to 'immune amnesia'

Figures from a study released Nov. 1 in the journal Science illustrate the how measles eliminates the immune system's memory.
American Association for the Advancement of Science
Figures from a study released Nov. 1 in the journal Science illustrate the how measles eliminates the immune system's memory.

New research is showing signs that a measles infection can produce what specialists call “immune amnesia.” WXXI’s Brett Dahlberg has more with an infectious disease expert at Rochester General Hospital.

New research has shown signs that a measles infection can produce an “immune amnesia” effect.Emil Lesho, an infectious disease physician and epidemiologist at Rochester Regional Health, said the research shows that the harms of a measles infection last well past when the body seems to beat the virus.

Figures from a study released Nov. 1 in the journal Science illustrate the how measles eliminates the immune system's memory.
Credit American Association for the Advancement of Science
/
American Association for the Advancement of Science
Figures from a study released Nov. 1 in the journal Science illustrate the how measles eliminates the immune system's memory.

“It impairs your body’s ability to fight new infections,” Lesho said. “And diseases that you already previously exposed to, it also impaired your ability to fight those, as well.”Lesho says the measles virus seems to indiscriminately attack a wide array of the body’s immune cells, and thereby erases “a good chunk” of the body’s memory of what infections it’s already beaten.

Two separate studies published Nov. 1,one in the journal Scienceandone in Science Immunology, are the basis of this new evidence.

Lesho said the measles virus is highly contagious, andlocal cases of measlesin the last year highlight the need for people to be vaccinated.

“It’s a big deal, because when a person that has measles comes into a clinic, if you’ve shared any air in a room with that person, that room has to be quarantined for two hours,” he said. “You have to evacuate,”even in situationswhere the virus is suspected but unconfirmed.

Vaccinating against measles does not cause any of the immune amnesia associated with actually getting the virus, Lesho said.

Copyright 2019 WXXI News

Brett is the health reporter and a producer at WXXI News. He has a master’s degree from the City University of New York Graduate School of Journalism and before landing at WXXI, he was an intern at WNYC and with Ian Urbina of the New York Times. He also produced freelance reporting work focused on health and science in New York City. Brett grew up in Bremerton, Washington, and holds a bachelor’s degree from Willamette University in Salem, Oregon.
Brett Dahlberg